The 4Kscore Test is recommended for men concerned with their risk for high-grade, aggressive prostate cancer and is especially useful when considering a prostate biopsy. The 4Kscore Test measures four biomarkers: total PSA, free PSA, intact PSA, and hK2. Blood test results along with factors such as a patient’s age, digital rectal exam, and prior biopsy results are combined in an algorithm to give physicians a personal risk score for each patient.
Unlike traditional PSA tests, the 4Kscore Test distinguishes men with a low risk for aggressive prostate cancer from those with a high risk. Individuals with a low-risk 4Kscore have a less than 1% chance of developing distant metastasis within the next 10 years. Physicians can identify patients with a high probability of having aggressive prostate cancer and offer appropriate treatment, while avoiding overtreatment of low-grade prostate cancer.
While the 4Kscore Test can’t provide a prostate cancer diagnosis, it can help physicians and their patients decide whether or not to perform a biopsy based on the probability of the patient having potentially life-threatening prostate cancer.
4Kscore Test highlights:
- Non-invasive
- Looks at four prostate-specific biomarkers
- Predicts risk of high-grade prostate cancer
- Predicts long-term risk of distant metastasis
- Reduces overtreatment and unnecessary biopsies
- Allows physicians to make better treatment decisions for their patients





